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Deadly Effects Of Acetaminophen With Overuse

By Sharon Folkner

There were a significant number of reports on the deadly effects of acetaminophen that were enough to catch the attention of the Food and Drug Administration back in 2009. The agency then proposed to lower the dosage in order to reduce risks, as well as to begin labeling the boxes on possible liver damage if not taken exactly as prescribed.

This pain reliever has been considered the safest type of medication available on the market that helps to alleviate pain. When people started to take acetaminophen under the assumption that it was safe and okay to go above the maximum dose, the adverse effects on liver functions began to show.

Also commonly known as paracetamol, this drug has become almost a household name for treatment of fever and pain. This fact alone increases the risk of over dosage within a household setting, especially for children.

Many medications use acetaminophen as an added ingredient in their formulations in order to achieve maximum effect in symptomatic relief, especially for pain and fever during times of cold and cough. People are unaware that they may have already introduced acetaminophen into their system by taking one type of medication for a common cold, and then they decide to take acetaminophen in a concentrated dosage form for a migraine headache, for example. Unwittingly, they have overdosed the acetaminophen and this could lead to bigger and more lethal complications.

The main effect that over dosage of acetaminophen can have is on the liver, and this is caused when compounds (metabolites) in the chemical structure tend to overwhelm the pathways of gluthathione in the liver. This essential antioxidant, glutathione, is needed for protection of cells from things like free radicals and peroxide toxins that can make it to the liver due to bad lifestyle eating habits and alcohol intake.

Deterioration or degeneration of cell structures as a result of low levels of glutathione due to the weakening of production can then result in physically manifested symptoms, causing a person to literally waste away gradually. Such examples of cell deterioration can be seen in AIDS and cancer patients whose diseases are at the cellular level of severity, and have complicated treatment methods in order to simply lengthen the life span with no real guarantees for a reversal of the condition.

However, in many scientific communities, it is believed that glutathione can actually stop or reverse the degeneration of cells, as long as one can raise the level of the presence of glutathione in the body. This, however, may be very difficult to achieve, and although there are supplements that do contribute to glutathione or antioxidant level upgrades, this may not be enough in terms of concentration to really treat symptomatic patients.

Large doses of acetaminophen can and will affect the liver functions, due to the fact that the drug is automatically directed there during its process. The damage is then made worse if the accumulation of the drug begins to take on added chemical reactions which tend to have severely adverse effects on the liver function.

The lifestyle trends today encourage alcohol intake for people of age, and intake of other unhealthy processed foods that can lead to excessive damage to the liver even on their own. When combined with acetaminophen in excessive daily dosages, this can be a lethal combination for those who choose to self medicate without consulting a health professional.

The signs of liver damage are usually seen in darkening of urine color, right upper abdominal pain, yellow tinge in the whites of the eyes, and pale stools. It is best to consult a doctor immediately and inform him of any history of possible consistent acetaminophen use by listing all the possible medications on one’s regular treatment regimen.

Learn more about How to Live Longer & Better. Stop by Sharon Folkner’s site where you can find out all about Exuberant Health and what it can do for you.

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Article Citation
MLA Style Citation:
Folkner, Sharon "Deadly Effects Of Acetaminophen With Overuse." Deadly Effects Of Acetaminophen With Overuse. 26 Aug. 2010. 19 Sep 2017 <>.

APA Style Citation:
Folkner, S (2010, August 26). Deadly Effects Of Acetaminophen With Overuse. Retrieved September 19, 2017, from

Chicago Style Citation:
Folkner, Sharon "Deadly Effects Of Acetaminophen With Overuse"

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