By Erin Matlock
Patients suffering from attention deficit hyperactivity disorder, or ADHD, participated in a pioneering study led by Nora Volkow, the Director at the National Institute on Drug Abuse and collaborator at Brookhaven National Laboratory. For the first time, evidence showed lower levels of dopamine in the areas of the brain involved with motivation and reward.
97 total participants were broken into two groups – 44 adults showing no signs or symptoms of ADHD and 53 patients who were diagnosed with the disorder but who had not previously received treatment. Positron emission tomography, or PET scans were used to measure the levels of two unique dopamine system markers – transporters and receptors.
Dopamine transporters are involved in the recycling and uptake of excess after the reward signal is sent, while dopamine receptors are crucial in the propagation of the reward signal.
While lying in a PET scanner, participants were injected with radiotracer, a radioactive compound designed to bind to a specific target. Multiple radiotracers were employed to account for the range of targets that were measured. The researchers used the data to determine the location and concentration of the dopamine receptors and transporters.
The findings indicated that patients with ADHD have smaller amounts of dopamine transporters and receptors in two regions of the brain – the midbrain and accumbens – two areas that are responsible for motivation and reward processes. Scientists also found that the markers showed high correlation with symptoms of adult ADHD, such as inability to focus and inattention.
The research showed, according to Volkow, that lower amounts of dopamine transporters and receptors play specific roles in the patients’ decreased attention and may underlie ADHD sufferers’ reactions to reward. She also added that results from the study supported the use of stimulants which increases dopamine levels in the brain thus, increasing the attention level of ADHD patients to mental tasks presented to them.
Article kindly provided by UberArticles.com
Topics: Psychology | Comments Off
MLA Style Citation:
Matlock, Erin "Symptoms Of ADHD: Why Your Brain Lacks Motivation." Symptoms Of ADHD: Why Your Brain Lacks Motivation. 24 Jun. 2010. uberarticles.com. 3 May 2015 <http://uberarticles.com/reference-and-education/psychology/symptoms-of-adhd-why-your-brain-lacks-motivation/>.
APA Style Citation:
Matlock, E (2010, June 24). Symptoms Of ADHD: Why Your Brain Lacks Motivation. Retrieved May 3, 2015, from http://uberarticles.com/reference-and-education/psychology/symptoms-of-adhd-why-your-brain-lacks-motivation/
Chicago Style Citation:
Matlock, Erin "Symptoms Of ADHD: Why Your Brain Lacks Motivation" uberarticles.com. http://uberarticles.com/reference-and-education/psychology/symptoms-of-adhd-why-your-brain-lacks-motivation/
Comments are closed.
Uber Articles and its partner sites cannot be held responsible for either the content nor the originality of any articles. If you believe the article has been stolen from you without your permission, please contact us and we will remove it immediately. If you have a problem with the accuracy or otherwise of the content of an article, please contact the author, not us! Also, please remember that any opinions and ideas presented in any of the articles are those of the author and cannot be taken to represent the opinions of Uber Articles. All articles are provided for informational purposes only. None of them should be relied upon for medical, psychological, financial, legal, or other professional advice. If you need professional advice, see a professional. We cannot be held responsible for any use or misuse you make of the articles, nor can we be held responsible for any claims for earnings, cures, or other results that the article might make.